Take 1 capsule daily with food, preferably with breakfast, every day during your antibiotic course and for a few days afterwards or until the pack has been completed. Can be taken at the same time as antibiotics - strains in this product have been clinically trialled alongside antibiotics and found to reach the gut alive. Drink plenty of water with your course of live cultures. For anyone unable to swallow capsules, open and mix contents of the capsule with a cool meal or beverage.